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Proteogenomic analysis identifies neoantigens and bacterial peptides as immunotherapy targets in colorectal cancer

Considerable progress has recently been made in cancer immunotherapy, including immune checkpoint blockade, cancer vaccine, and adoptive T cell methods. The lack of effective targets is a major cause of the low immunotherapy response rate in colorectal cancer (CRC). Here, we used a proteogenomic str...

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Principais autores: Pengju Yao, Mingjie Gao, Weiyi Hu, Jiahao Wang, Yuhao Wang, Qingsong Wang, Jianguo Ji
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-06-01
Serier:Pharmacological Research
Fag:
Immunopeptidome
Colorectal cancer
Neoantigen
Bacterial peptides
Mass spectrometry
Immunotherapy
Online adgang:http://www.sciencedirect.com/science/article/pii/S1043661824001531
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