Towards accurate exclusion of neonatal bacterial meningitis: a feasibility study of a novel 16S rDNA PCR assay

Abstract Background PCRctic is an innovative assay based on 16S rDNA PCR technology that has been designed to detect a single intact bacterium in a specimen of cerebro-spinal fluid (CSF). The assay’s potential for accurate, fast and inexpensive discrimination of bacteria-free CSF makes it an ideal a...

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Autori principali:	Arthur Abelian, Thomas Mund, Martin D. Curran, Stuart A. Savill, Nipa Mitra, Carol Charan, Amanda L. Ogilvy-Stuart, Hugh R. B. Pelham, Paul H. Dear
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2020-06-01
Serie:	BMC Infectious Diseases
Soggetti:	Neonatal bacterial meningitis Broad-range PCR Ethidium monoazide
Accesso online:	http://link.springer.com/article/10.1186/s12879-020-05160-x
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