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Follicular lymphoma-associated mutations in the V-ATPase chaperone Vma21 activate autophagy by dysfunctional V-ATPase assembly

A significant number of follicular lymphoma patients display recurrent mutations in subunits and regulators of the vacuolar-type H+-translocating ATPase (V-ATPase). Past studies focusing on the role of these mutations highlighted essential functions of macroautophagy/autophagy, amino-acid, and nutri...

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Bibliografske podrobnosti
Principais autores: Ying Yang, Zhihai Zhang, Daniel J. Klionsky
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis Group 2022-12-01
Serija:Autophagy Reports
Teme:
Online dostop:http://dx.doi.org/10.1080/27694127.2022.2077509
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