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Octreotide Does Not Inhibit Proliferation in Five Neuroendocrine Tumor Cell Lines

Somatostatin analogs (SSA) are well-established antisecretory drugs in functionally active neuroendocrine tumors (NET). Two placebo-controlled trials have recently demonstrated significant improvement of progression-free survival under SSA treatment. Furthermore, somatostatin receptor (SSTR) overexp...

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Principais autores: Samantha Exner, Vikas Prasad, Bertram Wiedenmann, Carsten Grötzinger
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-04-01
coleção:Frontiers in Endocrinology
Assuntos:
neuroendocrine tumor
somatostatin receptor
somatostatin analog
cell line
octreotide
radiation sensitivity
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fendo.2018.00146/full
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