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Combination Low Dose Tissue Type-Plasminogen Activator plus Annexin A2 for Improving Thrombolytic Stroke Therapy

Risk of hemorrhagic transformation, incomplete reperfusion, neurotoxicity and a short treatment time window comprise major challenges for tissue plasminogen activator (tPA) thrombolytic stroke therapy. Improving tPA therapy has become one of the highest priorities in the stroke field. This mini revi...

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Principais autores: Yinghua eJiang, Xiang eFan, Zhanyang eYu, Zhengbu eLiao, Xiao-Shu eWang, Klaus evan leyen, Xiaochuan eSun, Eng H Lo, Xiaoying eWang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015-10-01
Serier:Frontiers in Cellular Neuroscience
Fag:
Annexin A2
Rats
cerebral ischemia
Tissue type plasminogen activator
thrombolysis; combination therapy
focal embolic stroke model
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00397/full
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