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Optochemical elucidation of a critical role of the incomplete spindle assembly checkpoint in zebrafish development

Abstract Early animal embryos must balance the efficiency with the accuracy of mitotic control. However, the extent of mitotic errors that can be safely endured at different stages of development is unclear. In this study, using a recently developed photoswitchable CENP-E inhibitor, we introduce tra...

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Autores principales: Akira Matsura, Miyu Hosono, Kazuya Matsuo, Nobuyuki Tamaoki, Tomoya Kotani, Ryota Uehara
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Portfolio 2026-03-01
Colección:Communications Biology
Acceso en línea:https://doi.org/10.1038/s42003-026-09871-w
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