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Structural insights into cannabinoid receptors CB1 and CB2: determinants of ligand selectivity

Cannabinoid receptors 1 (CB1) and 2 (CB2) are key components of the endocannabinoid system and play central roles in regulating diverse physiological processes, including neural signaling, immune modulation, and inflammation. Both receptors belong to the Class A G protein-coupled receptor (GPCR) fam...

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Autors principals: Ann Varghese, Jie Liu, Wenjing Guo, Tucker A. Patterson, Huixiao Hong
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2026-05-01
Col·lecció:Frontiers in Chemical Biology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fchbi.2026.1830007/full
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