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Generation of a transparent killifish line through multiplex CRISPR/Cas9mediated gene inactivation

Body pigmentation is a limitation for in vivo imaging and thus for the performance of longitudinal studies in biomedicine. A possibility to circumvent this obstacle is the employment of pigmentation mutants, which are used in fish species like zebrafish and medaka. To address the basis of aging, the...

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Autors principals: Johannes Krug, Birgit Perner, Carolin Albertz, Hanna Mörl, Vera L Hopfenmüller, Christoph Englert
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications Ltd 2023-02-01
Col·lecció:eLife
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Accés en línia:https://elifesciences.org/articles/81549
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