Immuno-stimulation by OX40 ligand transgenic Ewing sarcoma cells

Interleukin-2 (IL-2) transgenic Ewing sarcoma cells can induce tumor specific T and NK cell responses and reduce tumor growth in vivo and in vitro. Nevertheless, the efficiency of this stimulation is not high enough to inhibit tumor growth completely. In addition to recognition of the cognate antige...

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Bibliografiske detaljer

Principais autores:	Dajana eReuter, Martin Sebastian Staege, Caspar David Kühnöl, Juergen eFoell
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2015-10-01
Serier:	Frontiers in Oncology
Fag:	Immunotherapy Ewing sarcoma Co-stimulation OX40/OX40L system tumor necrosis factor (receptor) superfamily
Online adgang:	http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00242/full
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