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Adult Patients with Philadelphia-Positive B-Cell Acute Lymphoblastic Leukemia Treated with a Pediatric-Inspired Multiagent Chemotherapy Regimen, in Combination with a TKI, Do Not Require Routine alloSCT

Tyrosine kinase inhibitors (TKIs) added to chemotherapy have improved outcomes of adult patients with Philadelphia-positive B-cell acute lymphoblastic leukemia (Ph+ B-ALL). These improvements initially led to a larger proportion of patients realizing allogeneic stem cell transplantation (alloSCT), l...

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Autors principals: Donna Zhe Sian Eng, Fatima Khadadah, Maria Agustina Perusini, Eshrak Al-Shaibani, Eshetu G. Atenafu, Aniket Bankar, Marta Davidson, Guillaume Richard-Carpentier, Dawn Maze, Karen Yee, Aaron Schimmer, Vikas Gupta, Steven Chan, Dennis Dong Hwan Kim, Andre Schuh, Mark Minden, Hassan Sibai
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2026-02-01
Col·lecció:Current Oncology
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Accés en línia:https://www.mdpi.com/1718-7729/33/2/127
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