Current Approaches to the Preclinical Assessment of Endocrine Toxicity

Scientific relevance. Endocrine disruptors affect the functioning of endocrine organs, which leads to adverse drug reactions. Endocrine toxicity requires special attention in preclinical studies of candidate medicinal products.Aim. The study aimed to review international guidelines and approaches to...

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Autore principale:	D. A. Babkov
Natura:	Artigo
Lingua:	Russo
Pubblicazione:	Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2023-09-01
Serie:	Безопасность и риск фармакотерапии
Soggetti:	preclinical studies endocrine toxicity endocrine disruptors oecd guidance document 150 oestrogenic toxicity androgenic toxicity thyroid toxicity steroidogenesis
Accesso online:	https://www.risksafety.ru/jour/article/view/376
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