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Association between TNF-α (−308G > A) promoter polymorphism and HHV-6 DNA detection in a community-based Thai cohort

BackgroundHuman herpesvirus 6 (HHV-6) establishes lifelong latency after primary infection and may reactivate under conditions of immune modulation. Tumor necrosis factor alpha (TNF-α) is a key pro-inflammatory cytokine involved in antiviral responses, and functional variation in the TNF-α promoter...

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Gardado en:
Principais autores: Sureewan Bumrungthai, Sutida Pongpukdeesakul, Tipaya Ekalaksananan, Sureewan Duangjit, Chamsai Pientong, Nuchsupha Sunthamala
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2026-06-01
Series:Frontiers in Microbiology
Assuntos:
cytokine gene polymorphism
human herpesvirus 6 (HHV-6)
molecular epidemiology
TNF polymorphisms
viral latency and reactivation
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fmicb.2026.1825548/full
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