Clinical and treatment-related predictors of complete response after total neoadjuvant therapy for rectal cancer in a large multicenter analysis

Introduction: Complete response (CR) after total neoadjuvant therapy (TNT) in rectal cancer is linked to favorable local control and enables non-operative management (NOM). Achieving high CR rates is crucial. As no standard TNT protocol exists, we aimed to assess the impact of clinical factors and d...

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Bibliografiska uppgifter

Huvudupphov:	Georg W. Wurschi, Melanie Schneider, Jan-Niklas Becker, Bernd Frerker, Samuel M. Vorbach, Felix Ehret, Markus Diefenhardt, Fabian Schunn, Maria-Elena von Gruben, Marcel Büttner, Elgin Hoffmann, Alexander Rühle, Josephine Beier, Simone Ferdinandus, Maike Trommer, Ezgi Ceren Sahin, Julian Hlouschek, Kynann Aninditha, Daphne Schepers von Ohlen, Justus Kaufmann, Alina Depardon, Hai Minh Ha, Christopher Kessler, Adrianna Cieslak, Simon Trommer, Alexander Fabian, Mathias Sonnhoff, Florian Rißner, Maximilian Römer, Klaus Pietschmann
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Elsevier 2026-05-01
Serie:	Clinical and Translational Radiation Oncology
Ämnen:	Total neoadjuvant therapy TNT Chemoradiotherapy Rectal cancer Complete response Smoking
Länkar:	http://www.sciencedirect.com/science/article/pii/S2405630826000157
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