Inosine Triphosphate Pyrophosphatase (ITPase): Functions, Mutations, Polymorphisms and Its Impact on Cancer Therapies
Inosine triphosphate pyrophosphatase (ITPase) is an enzyme encoded by the <i>ITPA</i> gene and functions to prevent the incorporation of noncanonical purine nucleotides into DNA and RNA. Specifically, the ITPase catalyzed the hydrolysis of (deoxy) nucleoside triphosphates ((d) NTPs) into the corresp...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI AG
2022-01-01
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| Серии: | Cells |
| Предметы: | |
| Online-ссылка: | https://www.mdpi.com/2073-4409/11/3/384 |
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