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Mapping cis- and trans-regulatory target genes of human-specific deletions

Abstract Deletion of functional sequence is predicted to represent a fundamental mechanism of molecular evolution. Comparative genetic studies of primates have identified thousands of human-specific deletions (hDels), and the cis-regulatory potential of short (≤31 base pairs) hDels has been assessed...

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Auteurs principaux: Tyler Fair, Bryan J. Pavlovic, Dani Swope, Octavio E. Castillo, Nathan K. Schaefer, Alex A. Pollen
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2025-12-01
Collection:Nature Communications
Accès en ligne:https://doi.org/10.1038/s41467-025-67424-x
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