Clinical validation of a multi-model blood cfDNA methylation assay for early-stage gastrointestinal cancer screening

Background: Gastrointestinal (GI) tract cancers are the second leading cause of cancer-related mortality, often due to late detection. There is a critical need for non-invasive, highly sensitive biomarkers for early-stage cancer and precancerous lesion detection to enable timely intervention. This s...

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Autors principals:	Lingqin Zhu, Shuye Lin, Junfeng Xu, Jianwei Yu, Fangli Men, Dongliang Yu, Xianzong Ma, Ju Tian, Hui Xie, Linghui Duan, Xin Wang, Shuyang Sun, Chenguang Li, Shu Li, Qian Kang, Mengyu Jia, Xueqin Lin, Qiaoqiao Lin, Lijuan Lin, Xiang Yi, Ruiru Wang, Wei Guo, Xueqing Gong, Jianqiu Sheng, Ni Guo, Shiqian Lan, Peng Jin, Yuqi He
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2026-07-01
Col·lecció:	Journal of Advanced Research
Matèries:	Gastrointestinal cancers Cell-free DNA methylation Diagnosis prediction Cancer signal origin
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S209012322500832X
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