Morphological, electrophysiological, and molecular alterations in foetal noncompacted cardiomyopathy induced by disruption of ROCK signalling

Left ventricular noncompaction cardiomyopathy is associated with heart failure, arrhythmia, and sudden cardiac death. The developmental mechanism underpinning noncompaction in the adult heart is still not fully understood, with lack of trabeculae compaction, hypertrabeculation, and loss of prolifera...

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Principais autores:	David Sedmera, Veronika Olejnickova, Barbora Sankova, Hana Kolesova, Martin Bartos, Alena Kvasilova, Lauren C. Phillips, Simon D. Bamforth, Helen M. Phillips
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-10-01
coleção:	Frontiers in Cell and Developmental Biology
Assuntos:	mouse embryonic heart ventricular wall myocardial trabeculae compaction conduction cardiomyocyte proliferation
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcell.2024.1471751/full
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