Zika virus infections of human stem cell-derived cerebral organoids reveal viral lineage-specific pathogenesis responses

ABSTRACT Zika virus (ZIKV) has multiple lineages and strains that cause a range of disease severity, underscoring the need to elucidate differential neuropathogenesis mechanisms. Here, we performed systematic, side-by-side comparisons of African, Asian, and American ZIKV lineage infections using cer...

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Principais autores:	Alfred T. Harding, Yichen Zhang, Jane-Jane Chen, Jenna M. Antonucci, Alexsia Richards, Valerie Leger, Charles A. Whittaker, Yann S. Vanrobaeys, Divyansh Agarwal, Tenzin Lungjangwa, Rudolf Jaenisch, Lee Gehrke
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology 2026-07-01
סדרה:	mBio
נושאים:	virus organoid pathogenesis Zika flavivirus stress response
גישה מקוונת:	https://journals.asm.org/doi/10.1128/mbio.00863-26
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