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MegaPath: sensitive and rapid pathogen detection using metagenomic NGS data

Abstract Background Next-generation sequencing (NGS) enables unbiased detection of pathogens by mapping the sequencing reads of a patient sample to the known reference sequence of bacteria and viruses. However, for a new pathogen without a reference sequence of a close relative, or with a high load...

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Principais autores: Chi-Ming Leung, Dinghua Li, Yan Xin, Wai-Chun Law, Yifan Zhang, Hing-Fung Ting, Ruibang Luo, Tak-Wah Lam
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-12-01
Colecção:BMC Genomics
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Acesso em linha:https://doi.org/10.1186/s12864-020-06875-6
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