Tie2 as a novel key factor of microangiopathy in systemic sclerosis
Abstract Background The angiopoietin(Ang)/Tie2 system is a key regulator of vascular biology. The expression of membrane bound (mb) Tie2 and Ang-1 ensures vessel stability, whereas Ang-2, inducible by vascular endothelial growth factor (VEGF), hypoxia, and inflammation, acts as an antagonist. Tie2 s...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BMC
2017-05-01
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| Seri Bilgileri: | Arthritis Research & Therapy |
| Konular: | |
| Online Erişim: | http://link.springer.com/article/10.1186/s13075-017-1304-2 |
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