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Evolutionary analysis of polyproline motifs in Escherichia coli reveals their regulatory role in translation.

Translation of consecutive prolines causes ribosome stalling, which is alleviated but cannot be fully compensated by the elongation factor P. However, the presence of polyproline motifs in about one third of the E. coli proteins underlines their potential functional importance, which remains largely...

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Bibliografski detalji
Glavni autori: Fei Qi, Magdalena Motz, Kirsten Jung, Jürgen Lassak, Dmitrij Frishman
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2018-02-01
Serija:PLoS Computational Biology
Online pristup:https://doi.org/10.1371/journal.pcbi.1005987
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