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TRIM19/PML Restricts HIV Infection in a Cell Type-Dependent Manner

The promyelocytic leukemia protein (PML) is the main structural component of the nuclear matrix structures termed nuclear domain 10 (ND10) or PML nuclear bodies (PML-NBs). PML and ND10 structures have been shown to mediate an intrinsic immune response against a variety of different viruses. Their ro...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Tanja Kahle, Bianca Volkmann, Kristin Eissmann, Alexandra Herrmann, Sven Schmitt, Sabine Wittmann, Laura Merkel, Nina Reuter, Thomas Stamminger, Thomas Gramberg
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2015-12-01
Schriftenreihe:Viruses
Schlagworte:
PML
TRIM19
ND10
HIV-1
retrovirus
intrinsic immunity
Online-Zugang:http://www.mdpi.com/1999-4915/8/1/2
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