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Insulin-like growth factor binding proteins: a structural perspective

Insulin-like growth factor binding proteins (IGFBP-1 to -6) bind insulin-like growth factors-I and -II (IGF-I and IGF-II) with high affinity. These binding proteins maintain IGFs in the circulation and direct them to target tissues, where they promote cell growth, proliferation, differentiation and...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Briony eForbes, Peter eMcCarthy, Raymond eNorton
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2012-03-01
Schriftenreihe:Frontiers in Endocrinology
Schlagworte:
Online-Zugang:http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00038/full
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