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Broad‐Spectrum Engineered Multivalent Nanobodies Against SARS‐CoV‐1/2

Abstract SARS‐CoV‐2 Omicron sublineages escape most preclinical/clinical neutralizing antibodies in development, suggesting that previously employed antibody screening strategies are not well suited to counteract the rapid mutation of SARS‐CoV‐2. Therefore, there is an urgent need to screen better b...

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Kaydedildi:
Asıl Yazarlar: Zhihong Wang, Zhuangzhuang Shi, Xiaochen Liao, Guiqi Quan, Hui Dong, Pinnan Zhao, Yangyihua Zhou, Ning Shi, Jie Wang, Yahui Wu, Chunxia Qiao, Xin ying Li, Ran Zhang, Zekun Wang, Tiecheng Wang, Xiang Gao, Jiannan Feng, Longlong Luo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley 2024-12-01
Seri Bilgileri:Advanced Science
Konular:
antibody engineering
de novo design
multivalent nanobodies
nanobody
SARS‐CoV‐1
SARS‐CoV‐2
Online Erişim:https://doi.org/10.1002/advs.202402975
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