Comparative analysis of gut microbiota in children with obstructive sleep apnea: assessing the efficacy of 16S rRNA gene sequencing in metabolic function prediction based on weight status

BackgroundAnalyzing bacterial microbiomes consistently using next-generation sequencing (NGS) is challenging due to the diversity of synthetic platforms for 16S rRNA genes and their analytical pipelines. This study compares the efficacy of full-length (V1–V9 hypervariable regions) and partial-length...

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Autori principali:	Hai-Hua Chuang, Chung-Guei Huang, Shih-Hsuan Chou, Hsueh-Yu Li, Chin-Chia Lee, Li-Ang Lee
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2024-06-01
Serie:	Frontiers in Endocrinology
Soggetti:	gut microbiome synthetic 16S rRNA gene read lengths analysis pipelines Firmicutes/Bacteroidetes ratio obesity
Accesso online:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1344152/full
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