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Machine learning-based single-sample molecular classifier for cancer grading

Tumor subtyping based on morphological grade is used in cancer treatment and management decision-making and to determine a patient’s prognosis. While low- and high-grade tumors are predictive of patient survival for many cancers, tumors of intermediate morphological grades are considered unreliable...

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Autori principali: Zoia Antysheva, Nikita Kotlov, Mariia V. Guryleva, Ivan Valiev, Viktor Svekolkin, Anna Belozerova, Sheila T. Yong, Dmitry Tabakov, Alexander Bagaev, Vladimir Kushnarev
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2025-07-01
Serie:Frontiers in Oncology
Soggetti:
molecular grade
gene expression
tumor grade
tumor cell differentiation
risk assessment
cancer diagnostics
Accesso online:https://www.frontiersin.org/articles/10.3389/fonc.2025.1617898/full
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