Synthesis of New Bis-Alkylated Phosphono Alkenyl Acyclonucleosides : (Z) and (E)-Diethyl-2-(3-alkyl pyrimidin-1-yl)ethylen-1-yl Phosphonate

The E- and Z- phosphonoalkenyl acyclonucleosides of uracil and thymine were synthesized under Michael addition conditions. Introduction of an alkyl, alkenyl or alkynyl group at the N-3 position of the pyrimidine moiety was accomplished using potassium carbonate in DMF.

書誌詳細

主要な著者:	J. L. Imbach, J. L. Barascut, H. B. Lazrek, M. Taourirte, A. Rochdi
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2000-10-01
シリーズ:	Molecules
主題:	Acyclonucleoside Phophonoalkenyl Michael addition N-3-alkylation
オンライン･アクセス:	http://www.mdpi.com/1420-3049/5/10/1139/
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