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Growth-rate dependence reveals design principles of plasmid copy number control.

Genetic circuits in bacteria are intimately coupled to the cellular growth rate as many parameters of gene expression are growth-rate dependent. Growth-rate dependence can be particularly pronounced for genes on plasmids; therefore the native regulatory systems of a plasmid such as its replication c...

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Bibliografiske detaljer
Hovedforfatter: Stefan Klumpp
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2011-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3103578?pdf=render
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