Prefusion-stabilized SARS-CoV-2 S2-only antigen provides protection against SARS-CoV-2 challenge

Abstract Ever-evolving SARS-CoV-2 variants of concern (VOCs) have diminished the effectiveness of therapeutic antibodies and vaccines. Developing a coronavirus vaccine that offers a greater breadth of protection against current and future VOCs would eliminate the need to reformulate COVID-19 vaccine...

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Bibliografische Detailangaben

Hauptverfasser:	Ching-Lin Hsieh, Sarah R. Leist, Emily Happy Miller, Ling Zhou, John M. Powers, Alexandra L. Tse, Albert Wang, Ande West, Mark R. Zweigart, Jonathan C. Schisler, Rohit K. Jangra, Kartik Chandran, Ralph S. Baric, Jason S. McLellan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2024-02-01
Schriftenreihe:	Nature Communications
Online-Zugang:	https://doi.org/10.1038/s41467-024-45404-x
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