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A cryptic third active site in cyanophycin synthetase creates primers for polymerization

Cyanophycin synthetase CphA1 polymerizes Asp and Arg into the nitrogen reserve polymer cyanophycin using two active sites. Sharon et al. show CphA1 has a cryptic 3rd active site that cleaves cyanophycin into primers for self-sufficient biosynthesis.

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Bibliografiska uppgifter
Huvudupphov: Itai Sharon, Sharon Pinus, Marcel Grogg, Nicolas Moitessier, Donald Hilvert, T. Martin Schmeing
Materialtyp: Artigo
Språk:Inglês
Utgiven: Nature Portfolio 2022-07-01
Serie:Nature Communications
Länkar:https://doi.org/10.1038/s41467-022-31542-7
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