Immune landscape of oncohistone-mutant gliomas reveals diverse myeloid populations and tumor-promoting function

Abstract Histone H3-mutant gliomas are deadly brain tumors characterized by a dysregulated epigenome and stalled differentiation. In contrast to the extensive datasets available on tumor cells, limited information exists on their tumor microenvironment (TME), particularly the immune infiltrate. Here...

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Bibliografiske detaljer

Principais autores:	Augusto Faria Andrade, Alva Annett, Elham Karimi, Danai Georgia Topouza, Morteza Rezanejad, Yitong Liu, Michael McNicholas, Eduardo G. Gonzalez Santiago, Dhana Llivichuzhca-Loja, Arne Gehlhaar, Selin Jessa, Antonella De Cola, Bhavyaa Chandarana, Caterina Russo, Damien Faury, Geoffroy Danieau, Evan Puligandla, Yuhong Wei, Michele Zeinieh, Qing Wu, Steven Hebert, Nikoleta Juretic, Emily M. Nakada, Brian Krug, Valerie Larouche, Alexander G. Weil, Roy W. R. Dudley, Jason Karamchandani, Sameer Agnihotri, Daniela F. Quail, Benjamin Ellezam, Liza Konnikova, Logan A. Walsh, Manav Pathania, Claudia L. Kleinman, Nada Jabado
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2024-09-01
Serier:	Nature Communications
Online adgang:	https://doi.org/10.1038/s41467-024-52096-w
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