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Automodified Poly(ADP-Ribose) Polymerase Analysisto Monitor DNA Damagein Peripheral Lymphocytes of Floriculturists Occupationally Exposed to Pesticides

Increased DNA damage and the propension to cancer development, depend on the modulation of the mechanisms to control and maintain genomic integrity. Poly(ADP-Ribose)Polymerase activation and automodification are early responses to genotoxic stress. Upon binding to DNA strand breaks, the enzyme, a mo...

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Main Authors: Serena Imperato, Carmela Mistretta, Maria Marone, Ilaria Migliaccio, Ilaria Pulcinelli, Maria Rosaria Faraone Mennella
Format: Artigo
Language:Inglês
Published: MDPI AG 2019-02-01
Series:Cells
Subjects:
Poly(ADP-Ribose)Polymerase
automodified PARP (PAR-PARP)
DNA damage
pesticides
growers
greenhouses
Online Access:https://www.mdpi.com/2073-4409/8/2/137
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