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Cilostazol attenuates ovariectomy-induced bone loss by inhibiting osteoclastogenesis.

Cilostazol has been reported to alleviate the metabolic syndrome induced by increased intracellular adenosine 3',5'-cyclic monophosphate (cAMP) levels, which is also associated with osteoclast (OC) differentiation. We hypothesized that bone loss might be attenuated via an action on OC by cilostazol....

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Autors principals: Ke Ke, Ali Muhammad Safder, Ok-Joo Sul, Jae-Hee Suh, Yeonsoo Joe, Hun-Taeg Chung, Hye-Seon Choi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2015-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC4436362?pdf=render
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