Generation of two human ISG15 knockout iPSC clones using CRISPR/Cas9 editing
Interferon stimulated gene 15 (ISG15) is one of the most highly upregulated proteins in response to viral infection and is involved in numerous pathways with multiple mechanisms of actions. ISG15 deficiency has been reported to induce type I interferonopathy owing to defective negative regulation of...
שמור ב:
| Principais autores: | , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Elsevier
2021-01-01
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| סדרה: | Stem Cell Research |
| גישה מקוונת: | http://www.sciencedirect.com/science/article/pii/S1873506120304360 |
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