Powerful and Real-Time Quantification of Antifungal Efficacy against Triazole-Resistant and -Susceptible Aspergillus fumigatus Infections in Galleria mellonella by Longitudinal Bioluminescence Imaging

ABSTRACT Aspergillus fumigatus is an environmental mold that causes life-threatening respiratory infections in immunocompromised patients. The plateaued effectiveness of antifungal therapy and the increasing prevalence of triazole-resistant isolates have led to an urgent need to optimize and expand...

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Autori principali:	Eliane Vanhoffelen, Lauren Michiels, Matthias Brock, Katrien Lagrou, Agustin Reséndiz-Sharpe, Greetje Vande Velde
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2023-08-01
Serie:	Microbiology Spectrum
Soggetti:	Galleria mellonella Aspergillus fumigatus antifungal screening bioluminescence imaging triazole resistance antifungal therapy
Accesso online:	https://journals.asm.org/doi/10.1128/spectrum.00825-23
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