Neoadjuvant metformin added to conventional chemotherapy synergizes anti-proliferative effects in ovarian cancer

Abstract Background Ovarian cancer is the leading cause of cancer-related death among women. Complete cytoreductive surgery followed by platinum-taxene chemotherapy has been the gold standard for a long time. Various compounds have been assessed in an attempt to combine them with conventional chemot...

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Detalhes bibliográficos

Principais autores:	Kuo-Chang Wen, Pi-Lin Sung, Alexander T. H. Wu, Ping-Chieh Chou, Jun-Hung Lin, Chi-Ying F. Huang, Sai-Ching J. Yeung, Mong-Hong Lee
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2020-08-01
coleção:	Journal of Ovarian Research
Assuntos:	Neoadjuvant metformin Ovarian cancer Clinically relevant dosage AKT/mTOR pathway Synergistic effects
Acesso em linha:	http://link.springer.com/article/10.1186/s13048-020-00703-x
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