The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs

GPR88 is an orphan G protein-coupled receptor (GPCR) considered as a promising therapeutic target for neuropsychiatric disorders; its pharmacology, however, remains scarcely understood. Based on our previous report of increased delta opioid receptor activity in Gpr88 null mice, we investigated the i...

Полное описание

Библиографические подробности

Главные авторы:	Thibaut Laboute, Jorge Gandía, Lucie P Pellissier, Yannick Corde, Florian Rebeillard, Maria Gallo, Christophe Gauthier, Audrey Léauté, Jorge Diaz, Anne Poupon, Brigitte L Kieffer, Julie Le Merrer, Jérôme AJ Becker
Формат:	Artigo
Язык:	Inglês
Опубликовано:	eLife Sciences Publications Ltd 2020-01-01
Серии:	eLife
Предметы:	in vitro pharmacology BRET experiments beta-arrestin GPCR oligomerisation knockout animals in vivo pharmacology
Online-ссылка:	https://elifesciences.org/articles/50519
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!