Sequential gene expression analysis of myelodysplastic syndrome transformation identifies HOXB3 and HOXB7 as the novel targets for mesenchymal cells in disease

Abstract Background Myelodysplastic syndrome (MDS) is known to arise through the pathogenic bone marrow mesenchymal stem cells (MSC) by interacting with hematopoietic stem cells (HSC). However, due to the strong heterogeneity of MDS patients, it is difficult to find common targets in studies with li...

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Principais autores:	Chunlai Yin, Yanqi Li, Cheng Zhang, Shizhu Zang, Zilong Wang, Xue Yan, Tonghui Ma, Xia Li, Weiping Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-01-01
Colecção:	BMC Cancer
Assuntos:	Myelodysplastic syndromes Mesenchymal stem cells Gene expression profiling Targets HOXB3 HOXB7
Acesso em linha:	https://doi.org/10.1186/s12885-024-11859-w
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