SYNTHESIS AND BIOLOGICAL EVALUATION OF 1H-(INDOLE-5-YL)-3-SUBSTITUTED-1,2,4-OXADIAZOLES AS NOVEL 5-LOX INHIBITORS
: A series of indolyloxadiazoles were synthesized from amidoxime and indole 3-carboxaldehyde using CAN as a catalyst and PEG as a solvent. In vitro, a 5-LOX inhibitory assay has been performed for all the synthesized compounds. Among the tested compounds, 4bf showed the highest potency (IC50 18.78 µ...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , |
|---|---|
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
Turkish Chemical Society
2024-02-01
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| মালা: | Journal of the Turkish Chemical Society, Section A: Chemistry |
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://dergipark.org.tr/tr/download/article-file/3292409 |
| ট্যাগগুলো: |
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