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Development of therapeutic-grade small interfering RNAs by chemical engineering

Recent successes in clinical trials have provided important proof of concept that small interfering RNAs indeed constitute a new promising class of therapeutics. Although great efforts are still needed to ensure efficient means of delivery in vivo, the siRNA molecule itself has been successfully eng...

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Hlavní autoři: Jesper Bertram Bramsen, Jørgen eKjems
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2012-08-01
Edice:Frontiers in Genetics
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On-line přístup:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00154/full
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