Flavonoid Derivatives as Potential Cholinesterase Inhibitors in Scopolamine-Induced Amnesic Mice: An In Vitro, In Vivo and Integrated Computational Approach

Flavonoids are one of the most exciting types of phenolic compounds with a wide range of bioactive benefits. A series of flavone derivatives (<b>F1</b>–<b>F5</b>) were previously synthesized from substituted O-hydroxy acetophenone and substituted chloro-benzaldehydes. The titled compounds <b>F1</b>–...

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Principais autores:	Fakhria A. Al-Joufi, Syed Wadood Ali Shah, Mohammad Shoaib, Mehreen Ghias, Shafiullah, Atif Ali Khan Khalil, Syed Babar Jamal, Syed Muhammad Hassan Shah, Muhammad Zahoor
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-06-01
coleção:	Brain Sciences
Assuntos:	flavones enzyme inhibition docking Alzheimer’s disease AChE nootropic agents
Acesso em linha:	https://www.mdpi.com/2076-3425/12/6/731
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