Luminal Fluid Motion Inside an In Vitro Dissolution Model of the Human Ascending Colon Assessed Using Magnetic Resonance Imaging

Knowledge of luminal flow inside the human colon remains elusive, despite its importance for the design of new colon-targeted drug delivery systems and physiologically relevant in silico models of dissolution mechanics within the colon. This study uses magnetic resonance imaging (MRI) techniques to...

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Hlavní autoři:	Connor O’Farrell, Caroline L. Hoad, Konstantinos Stamatopoulos, Luca Marciani, Sarah Sulaiman, Mark J. H. Simmons, Hannah K. Batchelor
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2021-09-01
Edice:	Pharmaceutics
Témata:	dynamic colon model (DCM) large intestine colon colon-specific drug formulations colonic flow phase contrast cine-MRI
On-line přístup:	https://www.mdpi.com/1999-4923/13/10/1545
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