Expression of a recombinant lactoferrin N-terminal functional fragment in three expression systems and its efficacy against enterotoxigenic Escherichia coli K88 infection

Abstract Background Lactoferrin (LF) is a multifunctional iron-binding glycoprotein with antimicrobial and immunomodulatory properties. Its significant antimicrobial activity and negligible toxic side effects make it a potential therapeutic agent for antibacterial use. However, LF’s in vivo protecti...

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Autors principals:	Wei Li, Aoqian Fu, Wenbin Lu, Jiawei Chen, Baishi Lei, Wuchao Zhang, Kuan Zhao, Qingyan Li, Xin Li, Jingran Cheng, Yu Wang, Wanzhe Yuan
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2026-03-01
Col·lecció:	BMC Veterinary Research
Matèries:	Lactoferrin Pichia pastoris Saccharomyces cerevisiae Escherichia coli Staphylococcus aureus Antibacterial activity
Accés en línia:	https://doi.org/10.1186/s12917-026-05398-8
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