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Sestrin2 knockout exacerbates high-fat diet induced metabolic disorders and complications in female mice

Abstract Background Obesity and its associated complications raise significant public concern, revealing gender disparities in the susceptibility to metabolic disorders, with females often displaying greater resistance to obesity-related metabolic disorder than males. Sestrin2 is a crucial protein i...

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Main Authors: Le Zhang, Chengxia Kan, Junfeng Shi, Hongyan Qiu, Jingwen Zhang, Wenli Ding, Linfei Xu, Kexin Zhang, Zhentao Guo, Ningning Hou, Xiaodong Sun, Fang Han
Format: Artigo
Language:Inglês
Published: BMC 2024-08-01
Series:Nutrition & Metabolism
Subjects:
Sestrin2
Obesity
Female
UCP-1
Adipose tissue
Online Access:https://doi.org/10.1186/s12986-024-00834-8
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