Toxicity Mechanism of 2,3,7,8-Tetrachlorodibenzo-<i>p</i>-dioxin (TCDD) as Opportunity for Development of New Targeted Therapies Targeting Aryl Hydrocarbon Receptors (AhR)—Molecular Docking Simulation Study

<b>Background/Objectives</b>: 2,3,7,8-Tetrachlorodibenzo-<i>p</i>-dioxin (TCDD) is a highly toxic environmental contaminant whose adverse biological effects are primarily mediated through activation of the aryl hydrocarbon receptor (AhR). Upon ligand binding, AhR undergoes conformational changes tha...

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主要な著者:	Andrej Vuckovski, Darinka Gjorgieva Ackova
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2026-03-01
シリーズ:	Future Pharmacology
主題:	TCDD AhR PAS-B molecular docking competitive antagonist targeted therapy
オンライン･アクセス:	https://www.mdpi.com/2673-9879/6/1/15
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