Controlling the stereochemistry in 2-oxo-aldehyde-derived Ugi adducts through the cinchona alkaloid-promoted electrophilic fluorination

In this report, we introduce a new strategy for controlling the stereochemistry in Ugi adducts. Instead of controlling stereochemistry directly during the Ugi reaction we have attempted to stereodefine the chiral center at the peptidyl position through the post-Ugi functionalization. In order to ach...

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Detalles Bibliográficos

Principais autores:	Yuqing Wang, Gaigai Wang, Anatoly A. Peshkov, Ruwei Yao, Muhammad Hasan, Manzoor Zaman, Chao Liu, Stepan Kashtanov, Olga P. Pereshivko, Vsevolod A. Peshkov
Formato:	Artigo
Idioma:	Inglês
Publicado:	Beilstein-Institut 2020-08-01
Series:	Beilstein Journal of Organic Chemistry
Assuntos:	cinchona alkaloids electrophilic fluorination enantioselective synthesis 2-oxo-aldehydes ugi reaction
Acceso en liña:	https://doi.org/10.3762/bjoc.16.163
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