Apo[a] size and PNR explain African American-Caucasian differences in allele-specific apo[a] levels for small but not large apo[a]

Apolipoprotein [a] (apo[a]) gene size is a major predictor of lipoprotein [a] level. To determine genetic predictors of allele-specific apo[a] levels beyond gene size, we evaluated the upstream C/T and pentanucleotide repeat (PNR) polymorphisms. We determined apo[a] sizes, allele-specific apo[a] lev...

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Bibliografische Detailangaben

Hauptverfasser:	Jill Rubin, Han Jo Kim, Thomas A. Pearson, Steve Holleran, Rajasekhar Ramakrishnan, Lars Berglund
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2006-05-01
Schriftenreihe:	Journal of Lipid Research
Schlagworte:	lipoprotein [a] African Americans genotyping polymorphism apolipoprotein [a] pentanucleotide repeat
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S0022227520332466
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