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RNase H-dependent PCR (rhPCR): improved specificity and single nucleotide polymorphism detection using blocked cleavable primers

<p>Abstract</p> <p>Background</p> <p>The polymerase chain reaction (PCR) is commonly used to detect the presence of nucleic acid sequences both in research and diagnostic settings. While high specificity is often achieved, biological requirements sometimes necessitate that primers are placed in subo...

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Detaylı Bibliyografya
Asıl Yazarlar: Powers Kristy M, Rupp Susan M, Beltz Kristin R, Rose Scott D, Dobosy Joseph R, Behlke Mark A, Walder Joseph A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2011-08-01
Seri Bilgileri:BMC Biotechnology
Online Erişim:http://www.biomedcentral.com/1472-6750/11/80
Etiketler: Etiketle
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