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Switchable Retargeting of Lentiviral Vectors Through a VSV-G-Binding Adapter Molecule

Selective gene delivery to defined cell populations remains one of the key challenges in lentiviral vector-based gene therapy. The vesicular stomatitis virus glycoprotein (VSV-G) confers high infectivity but lacks cell-type specificity because of the ubiquitous expression of its receptor, LDLR. To e...

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Bibliografske podrobnosti
Principais autores: Vladislav A. Zhuchkov, Marat P. Valikhov, Yulia E. Kravchenko, Elena I. Frolova, Stepan P. Chumakov
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2025-11-01
Serija:Viruses
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Online dostop:https://www.mdpi.com/1999-4915/17/12/1563
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