HIV-1 Nef-induced lncRNA AK006025 regulates CXCL9/10/11 cluster gene expression in astrocytes through interaction with CBP/P300

Abstract Background HIV-associated neurocognitive disorder (HAND) is a neurodegenerative disease associated with persistent neuroinflammation and subsequent neuron damage. Pro-inflammatory factors and neurotoxins from activated astrocytes by HIV-1 itself and its encoded proteins, including the negat...

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Auteurs principaux:	Feng Zhou, Xiaomei Liu, Dongjiao Zuo, Min Xue, Lin Gao, Ying Yang, Jing Wang, Liping Niu, Qianwen Cao, Xiangyang Li, Hui Hua, Bo Zhang, Minmin Hu, Dianshuai Gao, Kuiyang Zheng, Yoshihiro Izumiya, Renxian Tang
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2018-10-01
Collection:	Journal of Neuroinflammation
Sujets:	HIV-associated neurocognitive disorder HIV-1 lncRNAs Astrocytes Nef CBP/P300
Accès en ligne:	http://link.springer.com/article/10.1186/s12974-018-1343-x
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